Environmental problems in the Donetsk region accumulate a long time, and negative changes in the environment become irreversible. Leading scientists of the region have increasingly raised the question of the negative impact of the ecological situation on human health. They pay attention to the fact that it is necessary to organize a clear monitoring system which will allow us to monitor the health status of people with the ecological situation to supply human security. It is necessary in order to develop a program of health prevention and environmental rehabilitation of the population of our region. Therefore, when assessing the impact of man-made environment on health it is more appropriate to define the overall loading of harmful compounds on our body.

    During the work the data on air quality, drinking water and soil of 20 cities and districts of Donetsk region has been collected [2,6].

    To make a complex assessment of environmental pollution on the human body the integral measure of general dangers of anthropogenic load (CL) was used. It was calculated as the arithmetic mean of integrated indicators of air pollution, soil and drinking water quality for all areas and a number of cities of Donetsk region [9,10].

CL = (Ka + Kw+Kp): N

    We know that the basic rate, which gives the integrate characteristics of health and shows the level of development and welfare of the state the best way is length of life.

    To estimate the pace of aging, surveys of young people 16-22 years old, who live in towns and districts of Donetsk region was carried out. To this aim, a survey of first-year students in the number of faculties of DonNTU was conducted for several years. About 350 boys and girls took part in this survey.

    Biological age (BW) was determined by the Kiev method [1] which provides a measure of biological age with the help of four technically simple, but quite informative indicators.

    There were fixed the weight of boys and girls (W), their blood pressure (ADF – systolic pressure), pulse pressure (ADP), the time of breath delay (TBD), the time of the static balancing (SB), a self-estimation of health through a special questionnaire (SQ), calculated on the basis of biological age and the rate of aging. The calculation of biological age (BA) performed according to formulas 1 (for boys) and 2 (for girls).

                                        BA = 27.0 + 0.22 * ADF – 0.15 * TBD * SB + 0,72 – 0,15 * SQ,                                       (1)

                                         BA = 1.46 + 0.42 * ADP + 0.25 * W * SB+ 0,70 – 0,14 * SQ.                                         (2)

    To determine the degree of aging of the organism such measure as the pace of aging was used. It is defined as the difference between biological and proper biological age of people. Proper biological age is the average population standard pace of aging. Calculations were carried out by the formulas 3 for boys and 4 – for girls.

                                                     NBA = 0.629 * HA + 18.6,                                                                         (3)

                                                       NBA = 0.581 * HA+ 17.3.                                                                         (4)

    By the pace of aging all boys and girls were divided into 5 groups. Data for groups are given in Table 1 .

    Table 1 - Ratio of individuals in groups, depending on the pace of aging.

    Picture 1 shows the ratio of groups of survey-participants by the pace of aging. Most of survey-participants (68%) belong to the 4th and 5th groups, that mean their body is aging rapidly. Percentage of people with the slower pace of aging is only 10%.

Picture 1 – The diagram of survey ratio depending on the pace of aging

(Animation includes 10 frames, the delay 100, the number of cycles 20, size 93,1 kB)

    Picture 2 shows the dependence of the pace of aging of the ecological situation in different areas of Donetsk region separately for girls and boys. Evidently the increase in the degree of environmental pollution causes an increase in the pace of aging. This mean a direct correlation among them. High correlation coefficients show a strong connection between these rates.

Picture 2 – Dependence of the pace of aging of the organism from the ecological situation

    This data confirm that the indicators of biological age and degree of aging of the human body can be used as a criterion for estimating the impact of the environment on human body.